For postprandial glucose-level control and metabolic syndrome, “Salacia” that inhibits sugar absorption as natural product, may be beneficial to a person.
“Salacia” which used to apply as Ayurvedic treatment against diabetes and obesity , is grown in India, Sri Lanka and South East Asia from ancient times.
Recently, we have found out a new function in “Salacia” as our research, “Salacia” has the properties to impede sugar and carbohydrate absorption and “Salacia” has contained a substance named “Salacinol” which is effective to inhibit α-glycosidase enzyme which is able to resolve from polysaccharide, glucan like starch into sugar.
Furthermore, “Salacia” has impeded sugar absorption on Maltose and Sucrose tolerance test, and we have confirmed reduction in fat and improvement in liver function by administrated “Salacia”.
- Polyphenol derivatives, including “ Salacinol (DASDES) Kotalanol, Mangiferin, Catechins and Tannins.
- For blood sugar level improvement and Obesity index improvement.
“Salacia” has inhibited the breakdown enzyme activity from oligosaccharides and polysaccharides into monosaccharide by competitive inhibition of α-glycosidase activity within lumen of the intestinal tract.
“Salacinol” (DASDES) and Kotalanol which are contained in “Salacia” as specific ingredient, have inhibited the enzyme activity of α-glucosidase.
| α-glucosidase | Salacinol | Kotalanol | Acarbose |
|---|---|---|---|
| Maltase | 3.20 | 2.80 | 1.30 |
| Sucrase | 0.84 | 0.58 | 1.10 |
| Isomaltase | 0.59 | 1.90 | 100.00 |
